Half-life reference / Library model input
Cagrilintide half-life
The PinPoint library stores 168 hours (7 days) for Cagrilintide. This is the input behind the arithmetic below, not a measurement of your levels or how long an effect lasts.
Clinical publication on cagrilintide with semaglutide, 2021: long-acting amylin analog context.
Library snapshot, 2026-10-05: CompoundLibrary.swift:667, halfLifeHours: 168. Read the cited reference.
Reading this particular reference
The library selects 168 hours, which equals seven days. The linked publication reports a cagrilintide half-life of 159 to 195 hours in its studied setting with semaglutide. A representative scalar within that interval makes a simple graph possible but does not preserve the whole distribution. Cagrilintide and semaglutide sharing a library scalar does not make their pharmacology, use, or individual time courses interchangeable.
The linked study reports 159 to 195 hours for cagrilintide in its studied setting. The library lists subcutaneous for tracking. A listed route is not proof that every input was measured through that route. The linked reference and its study context matter when interpreting the stored number.
Cagrilintide decay table
Starting at an arbitrary 100%, each elapsed half-life divides the remaining modeled amount by two. The calculation is 100 × 2 raised to the power of minus elapsed hours divided by 168. It describes a single contribution with no additional entries. The percentages are not percentages of benefit, receptor activity, or symptom relief.
| Half-lives | Hours | Days | Remaining (rounded) |
|---|---|---|---|
| 0 | 0 | 0 | 100.0% |
| 1 | 168 | 7 | 50.0% |
| 2 | 336 | 14 | 25.0% |
| 3 | 504 | 21 | 12.5% |
| 4 | 672 | 28 | 6.3% |
What the listed schedules mean mathematically
The library labels are Every 7 days. They describe available tracking patterns, not instructions. In an equal-input model, the limiting peak accumulation ratio is 1 ÷ (1 − 2 raised to minus interval divided by half-life). It compares a repeated pattern with one instantaneous input and assumes the same interval continues indefinitely.
- Every 7 days, if evenly spaced: 168 hours between entries; 50% of one contribution remains at that marker; limiting accumulation ratio 2.
About five half-lives here is 840 hours, or 35 days. Under the same linear assumptions, that is approximately the approach to steady state. Changing amounts, missed entries, irregular spacing and absorption change the pattern. The calculation does not decide when to start, stop, or change anything.
From a reference curve to a dose history
PinPoint’s Home curve models your levels between doses from published half-life data. Drag to scrub modeled values at any timestamp, or preview 30 days of a dose pattern. Log injections with compound, dose, site, and pain level, and backfill past doses so the history is complete from day one.
The graph on this page is simpler: it isolates exponential elimination so you can inspect the arithmetic. PinPoint’s modeled curves are mathematical visualizations of published population averages and do not account for individual variation. A modeled amount is not a laboratory concentration.
Explore dose logging in PinPoint or compare library half-life inputs.
Questions, answered
Is the half-life of Cagrilintide the same for everyone?
No. Half-life varies with the person, formulation and study context. The linked study reports 159 to 195 hours for cagrilintide in its studied setting. The stored number is a reference input, not a personal measurement.
How long until Cagrilintide clears?
With the stored 168-hour scalar, five half-lives take 840 hours (35 days), leaving 3.125% of one modeled starting contribution. Exponential decay never reaches exactly zero. This is not a detection window, a washout instruction, or proof that effects have ended.
What does steady state mean?
For unchanged, equally spaced inputs in a linear model, steady state means the pattern repeats from one interval to the next. About five half-lives gives roughly 97% of the limiting pattern. Peaks and troughs still occur; steady state does not mean a flat line or a recommended regimen.
PinPoint is a tracking and unit-conversion tool, not a medical device. Modeled levels are mathematical illustrations, not blood tests or individual predictions. Medical decisions belong with your healthcare provider.