Half-life reference / Library model input
Semaglutide half-life
Semaglutide is sold as Ozempic and Wegovy in injectable presentations, and as Rybelsus in an oral presentation. This page uses the subcutaneous library input. The PinPoint library stores 168 hours (7 days) for Semaglutide. This is the input behind the arithmetic below, not a measurement of your levels or how long an effect lasts.
DailyMed Ozempic prescribing information: terminal half-life approximately one week after subcutaneous administration.
Library snapshot, 2026-10-05: CompoundLibrary.swift:190, halfLifeHours: 168. Read the cited reference.
Reading this particular reference
The library uses a seven-day reference for the subcutaneous entry. A weekly interval and this half-life have the same duration, so the elementary decay calculation leaves half of one modeled contribution after seven days. This equality is arithmetic, not evidence that an individual follows the curve. The referenced label concerns an injected presentation; the number does not describe absorption of every formulation.
No numerical half-life range is given in the library source note. The library lists subcutaneous for tracking. A listed route is not proof that every input was measured through that route. The linked reference and its study context matter when interpreting the stored number.
Semaglutide decay table
Starting at an arbitrary 100%, each elapsed half-life divides the remaining modeled amount by two. The calculation is 100 × 2 raised to the power of minus elapsed hours divided by 168. It describes a single contribution with no additional entries. The percentages are not percentages of benefit, receptor activity, or symptom relief.
| Half-lives | Hours | Days | Remaining (rounded) |
|---|---|---|---|
| 0 | 0 | 0 | 100.0% |
| 1 | 168 | 7 | 50.0% |
| 2 | 336 | 14 | 25.0% |
| 3 | 504 | 21 | 12.5% |
| 4 | 672 | 28 | 6.3% |
What the listed schedules mean mathematically
The library labels are Every 7 days. They describe available tracking patterns, not instructions. In an equal-input model, the limiting peak accumulation ratio is 1 ÷ (1 − 2 raised to minus interval divided by half-life). It compares a repeated pattern with one instantaneous input and assumes the same interval continues indefinitely.
- Every 7 days, if evenly spaced: 168 hours between entries; 50% of one contribution remains at that marker; limiting accumulation ratio 2.
About five half-lives here is 840 hours, or 35 days. Under the same linear assumptions, that is approximately the approach to steady state. Changing amounts, missed entries, irregular spacing and absorption change the pattern. The calculation does not decide when to start, stop, or change anything.
From a reference curve to a dose history
PinPoint’s Home curve models your levels between doses from published half-life data. Drag to scrub modeled values at any timestamp, or preview 30 days of a dose pattern. Log injections with compound, dose, site, and pain level, and backfill past doses so the history is complete from day one.
The graph on this page is simpler: it isolates exponential elimination so you can inspect the arithmetic. PinPoint’s modeled curves are mathematical visualizations of published population averages and do not account for individual variation. A modeled amount is not a laboratory concentration.
Explore dose logging in PinPoint or compare library half-life inputs.
Questions, answered
Is the half-life of Semaglutide the same for everyone?
No. Half-life varies with the person, formulation and study context. No numerical half-life range is given in the library source note. The stored number is a reference input, not a personal measurement.
How long until Semaglutide clears?
With the stored 168-hour scalar, five half-lives take 840 hours (35 days), leaving 3.125% of one modeled starting contribution. Exponential decay never reaches exactly zero. This is not a detection window, a washout instruction, or proof that effects have ended.
What does steady state mean?
For unchanged, equally spaced inputs in a linear model, steady state means the pattern repeats from one interval to the next. About five half-lives gives roughly 97% of the limiting pattern. Peaks and troughs still occur; steady state does not mean a flat line or a recommended regimen.
PinPoint is a tracking and unit-conversion tool, not a medical device. Modeled levels are mathematical illustrations, not blood tests or individual predictions. Medical decisions belong with your healthcare provider.