What is MOTS-c, and what does a MOTS-c dosage chart answer?
MOTS-c, also searched as motsc, is a 16-amino-acid peptide whose code sits in a short open reading frame of mitochondrial DNA [1]. PinPoint's library lists it as research use only, logged by subcutaneous injection three or five times weekly, with a three-hour half-life input it labels a low-confidence tracking estimate and a 10 mg package example [2].
A mots-c dosage chart can answer exactly one kind of question well: given a vial total and a volume of liquid, where does an amount land on a syringe. It cannot answer what amount belongs in a person, because the source behind the compound never gave it to people. Keeping those two questions apart is the whole job of a chart page.
What did MOTS-c research actually measure?
The 2015 discovery paper identified MOTS-c and proposed that mitochondria release signaling peptides as well as making energy [1]. In cultured cells, MOTS-c acted on the folate cycle and purine synthesis, with activation of the energy sensor AMPK as part of the proposed mechanism.
In mice, the authors reported that MOTS-c treatment prevented age-dependent and high-fat-diet-induced insulin resistance and diet-induced obesity, with skeletal muscle identified as a main target tissue [1]. These are mouse endpoints under laboratory diets. The abstract reports no route-specific human pharmacokinetics, no human amount and no human outcome.
This is why the library's three-hour input is marked as an estimate rather than a measurement, and why its frequency labels, three times weekly and five times weekly, are logging options rather than findings [2]. A page that presents a MOTS-c dose in micrograms per kilogram for people is reaching beyond this source.
| Compound | Status | Half-life input | Package example |
|---|---|---|---|
| MOTS-c | Research use only, estimated model data | 3 h | 10 mg (vendor listing) |
How do you convert a 10 mg MOTS-c vial to syringe units?
The 10 mg package example divided by a hypothetical 2 mL final volume gives 5 mg/mL, or 5,000 mcg/mL [2][3]. Each U-100 unit is 0.01 mL, so each unit holds 0.05 mg, and 10 units hold 0.5 mg. At 1 mL, the same 10 units would hold 1 mg; at 3 mL, about 0.33 mg.
The 0.5 mg figure is one twentieth of the vial and was picked to show the scale, not taken from research. The MOTS-c dosing chart prints one fiftieth through one half of the vial against 1, 2 and 3 mL, and the MOTS-c calculator takes any vial size and volume. Both are conversion tools; neither selects an amount.
Unit boundaries need care with small peptides. Writing 0.5 mg as 500 mcg is the same quantity, but writing 500 mg by mistake is a thousandfold error that no syringe mark would reveal. Entering the vial in one unit and every later amount in the same unit keeps the decimal point where the arithmetic put it [3].
How do people log MOTS-c in PinPoint?
Three-times-weekly and five-times-weekly frequencies fit PinPoint's custom schedule option, with reminders tied to the day and time set [4][2]. Each entry records compound, dose, site and pain level, and site rotation suggests where the next injection goes [4].
With a three-hour input, the Home curve shows each entry as a short spike that returns close to baseline well before the next calendar day [2][4]. That shape is a mathematical visualization of an estimated input, not a published average or a measured level in the person using the app [4]. Backfilling past entries keeps the history complete from the first day.
Get PinPoint on the App StoreWhat do people ask about MOTS-c dosage?
- What is the MOTS-c half-life?
- The library uses three hours as a low-confidence tracking estimate. The discovery paper studied cells and mice and does not report a human half-life.
- What does a mots-c dosage chart show?
- It shows how amounts from a stated vial convert to millilitres and U-100 units at different liquid volumes. For a 10 mg vial in 2 mL, 10 units holds 0.5 mg. The chart is arithmetic and does not come from a human study.
- Has MOTS-c been tested in people?
- The library's source is a cell and mouse discovery study. It reports no human amount, route or outcome, which is why the entry is labeled research use only.
- Is motsc the same as MOTS-c?
- Yes. Motsc is a search spelling of MOTS-c, the mitochondrial open reading frame of the 12S rRNA type-c peptide. The library keeps one entry for both spellings.
- How many units is 0.5 mg of MOTS-c?
- For a 10 mg vial in 2 mL, the solution holds 5 mg/mL, so 0.5 mg is 0.1 mL, or 10 U-100 units. In 1 mL it would be 5 units, and in 3 mL 15 units.
Where do these facts come from?
Sources are listed by kind: labels first, then peer-reviewed papers, then PinPoint's own library, arithmetic and app description. Library values were retrieved from the PinPoint application on 5 October 2026; vendor listings support package sizes only.
- Discovery of the mitochondrial-derived peptide MOTS-c, 2015Cell Metab, 2015. Cell and mouse studies of metabolic homeostasis.Retrieved 2026-10-05 · study
- PinPoint compound library, application recordsHalf-life inputs, routes, frequencies, package examples and confidence labels as stored in the iOS app library and mirrored in the peptide guides.Retrieved 2026-10-05 · library
- Unit conversion arithmeticConcentration = amount / volume; volume = amount / concentration; U-100 units = mL x 100; remaining fraction = 2^(-elapsed / half-life).Retrieved 2026-10-05 · arithmetic
- PinPoint App Store descriptionFeature wording from the approved application description, not pricing.Retrieved 2026-10-05 · app-description