Peptides / Compound explainer

IGF-1 LR3: what the evidence covers and how the micrograms add up

IGF-1 LR3, also written LongR3-IGF-I, is a synthetic analogue of insulin-like growth factor I. The searches around it ask for a dosage, but the human literature on it is mostly about detecting it in blood, not about giving it. This page lays out that gap and then does the microgram arithmetic that a 1 mg vial requires.

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What is IGF-1 LR3, and what does an IGF-1 LR3 dosage query ask?

IGF-1 LR3 belongs to a group of synthetic IGF-I analogues, alongside R3-IGF-I and Des1-3 IGF-I, that anti-doping laboratories screen for in plasma [1]. It is not an approved medicine. PinPoint's library lists it as research use only, logged by subcutaneous injection, with a 24 hour half-life input marked low confidence and a 1 mg package example [2].

People searching igf lr3 dose or igf-1 long r3 dosage ask for a number and a frequency. The honest reply has two parts. First, no label and no human dosing study sit behind this compound in the library, so any number has to be read as arithmetic or as hearsay. Second, the arithmetic itself is unusually error-prone, because a 1 mg vial is normally discussed in micrograms and a slip of three decimal places is easy to make.

What do studies report about IGF-1 LR3?

The library's cited paper is a 2017 method study that detected LongR3-IGF-I, R3-IGF-I and Des1-3 IGF-I in human plasma using antibody capture and high-resolution mass spectrometry [1]. The authors note that superior pharmacokinetic properties have been described for these analogues compared with native IGF-I, which is part of why they are monitored in sport.

The same work studied breakdown in skin microsomes, in biological fluids and after administration of LongR3-IGF-I to rats. It identified several truncated metabolites, one of which roughly doubled the window in which LR3 use could be detected in the rodents [1]. That is a finding about analytical detectability, not a human elimination half-life.

The library therefore describes the 24 hour figure as a low-confidence tracking estimate rather than a measured human value [2]. Nothing in the cited source reports an amount given to people, a frequency or an outcome in people. A page that prints an IGF-1 LR3 dosage table is reporting something other than this evidence.

Library record for this compound
CompoundStatusHalf-life inputPackage example
IGF-1 LR3Research use only, estimated model data24 h1 mg (vendor listing)

How do you convert an IGF-1 LR3 vial from mg to mcg and units?

One milligram equals 1,000 micrograms. Dividing the 1 mg package example by a hypothetical 2 mL final volume gives 0.5 mg/mL, which is 500 mcg per mL [2][3]. On a U-100 syringe each unit is 0.01 mL, so each unit of that solution holds 5 mcg, and 10 units hold 50 mcg.

The 50 mcg row is chosen because it is a round fraction of the vial, one twentieth of 1,000 mcg, and makes the unit scale visible. It is not drawn from any study. Changing the volume rescales every mark: at 1 mL each unit is 10 mcg, and at 3 mL it is about 3.33 mcg [3]. The IGF-1 LR3 dosing chart prints these columns, and the IGF-1 LR3 calculator accepts entries in mg or mcg so the decimal point stays in one place.

1 mg = 1,000 mcg
1,000 mcg ÷ 2 mL = 500 mcg/mL = 5 mcg per unit
50 mcg ÷ 500 mcg/mL = 0.1 mL = 10 units
IGF-1 LR3: 1 mg in 2 mL, worked to U-100 units1 mg divided by 2 mL is 500 mcg per mL. 50 mcg is 0.1 mL, or 10 U-100 units. Arithmetic, not a dose. IGF-1 LR3: 1 MG IN 2 ML, WORKED TO U-100 UNITS 1 mg vial + 2 mL = 500 mcg/mL 50 mcg ÷ 500 mcg/mL = 0.1 mL = 10 units 0102030405060708090100 U-100 SCALE, 1 mL = 100 UNITS
Arithmetic illustration from stated inputs. Not a dose or a measured level.

How do people track IGF-1 LR3 entries in PinPoint?

The vial setup in PinPoint accepts vial size in mg, mcg or IU together with the water volume, and shows the concentration and syringe units immediately [4]. A visual fill-line guide covers 0.3, 0.5 and 1.0 mL insulin syringes, which matters for microgram-scale entries where 10 units is a short distance on the barrel [4].

Entries record compound, dose, site and pain level, and the schedule can be daily, every other day, weekly or custom, with reminders tied to the chosen day and time [4]. The Home curve models levels between doses from the library's 24 hour input [4][2], which is the low-confidence estimate described above.

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What do people ask about IGF-1 LR3?

Is IGF-1 LR3 the same as IGF-1?
No. IGF-1 LR3 is a synthetic analogue of insulin-like growth factor I, grouped by detection laboratories with R3-IGF-I and Des1-3 IGF-I. It is not an approved medicine, and the library lists it as research use only.
What is the half-life of IGF-1 LR3?
The library uses 24 hours as a low-confidence tracking estimate. The cited study measured detectability and metabolites in plasma and in rats, not a human elimination half-life.
How many mcg are in 10 units of IGF-1 LR3?
It depends on the volume. For a 1 mg vial in 2 mL, the solution holds 500 mcg/mL, so 10 units, or 0.1 mL, holds 50 mcg. In 1 mL it would be 100 mcg.
Is there a published IGF-1 LR3 dose for people?
None appears in the library's source. The cited paper is a detection method study and reports no human dosing, frequency or outcome.

Where do these facts come from?

Sources are listed by kind: labels first, then peer-reviewed papers, then PinPoint's own library, arithmetic and app description. Library values were retrieved from the PinPoint application on 5 October 2026; vendor listings support package sizes only.

  1. Mass spectrometry detection of LongR3-IGF-I and related analogues, 2017Growth Horm IGF Res, 2017. Plasma detection method, metabolism in vitro and in rats.Retrieved 2026-10-05 · study
  2. PinPoint compound library, application recordsHalf-life inputs, routes, frequencies, package examples and confidence labels as stored in the iOS app library and mirrored in the peptide guides.Retrieved 2026-10-05 · library
  3. Unit conversion arithmeticConcentration = amount / volume; volume = amount / concentration; U-100 units = mL x 100; remaining fraction = 2^(-elapsed / half-life).Retrieved 2026-10-05 · arithmetic
  4. PinPoint App Store descriptionFeature wording from the approved application description, not pricing.Retrieved 2026-10-05 · app-description